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By inhibiting NNMT, the body maintains higher NAD levels, which in turn activate SIRT1, a longevity-associated gene, which may improve mitochondrial activity, fat oxidation, insulin sensitivity, and by overall energy balance

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Peer-reviewed research has investigated AOD-9604 across animal models, ex vivo adipose tissue assays, and human clinical trials , with published studies appearing in journals including Endocrinology , the American Journal of Physiology Endocrinology and Metabolism , and Hormone Research