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Instead, DIC mediates electro-neutral exchange of dicarboxylates or GSH for inorganic phosphate ( TISSUE-SPECIFIC FEATURES OF GLUTATHIONE IMPORT TO MITOCHONDRIA Previous studies in a renal proximal tubular cell line, NRK-52E, indicated that overexpression of OGC and DIC increased mGSH levels and protected against oxidant-mediated cell death (Xu et al., 2006)

In contrast, in patients with congenital hypothyroidism in areas without iodine deficiency treated with 20-60 ug selenomethionine for 3 months (68), Se supplementation was found to reduce serum thyroglobulin