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Takahashi, K., Avissar, N., Whitin, J
It was previously reported that targeted FUS-induced BBB opening facilitates CNS penetration of systemically administered anti-A antibodies to targeted brain regions in the TgCRND8 and APP23 mouse model of AD, therefore reducing plaque load 5 , therefore confirms the feasibility of this strategy in promoting behavioral and memory recovery in a transgenic animal model 6,7
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