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Research has examined its cytoprotective effects across multiple tissue types including musculoskeletal, neural, and gastrointestinal systems

S-adenosylmethionine (SAMe), an amino acid derivative important in liver metabolism, and extracts from milk thistle ( Silybum marianum ), have been investigated (alone and in combination) in dogs for their liver-protecting properties and are currently used as part of treatment for a variety of liver diseases in dogs

They are essential for the normal functioning of muscles, nerves, blood cells and eyes