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Researchers found increased lung IL-4 and MMP-12 levels and decreased interferon- levels in Wistar rats after daily whole-body exposure to the smoke of 20 commercial unfiltered cigarettes six hours per day, five days per week, for three and one-half months (Xu et al

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Public health organisations should consider carefully the impact of discrimination and disadvantage on these kinds of risky health behaviours.' These findings are specific to the London-based study although the large, diverse sample studied means the results may be generalisable to other urban settings in the UK and elsewhere