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Lung Tissue Remodelling: Emerging research suggests GHK-Cu may have applications in treating fibrotic lung conditions by remodelling scar tissue and restoring healthier tissue architecture

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FDA staff's own briefing document, posted publicly ahead of the meeting as part of the docket, proposes that TB-500 (free base) and TB-500 acetate not be added to the list, citing incomplete physicochemical characterization, a lack of evidence of effectiveness for wound healing (including an in-vitro fibroblast study in which TB-500 reportedly did not induce wound healing), and insufficient nonclinical and clinical safety data

doi: 10.1136/ard-2022-223356 6 EdilovaMIAkramAAbdul-SaterAA