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There are eight members (GPX1GPX8) in mammalian GPX family ( 2+ in the labile iron pool ( c , a Na + -independent cystine/glutamate reverse transporter on the cell membrane ( c belongs to the heteromeric amino acid transporter family, which consists of two components linked by disulfide: the light-chain subunit solute carrier family 7 member 11 (SLC7A11) and the heavy-chain subunit solute carrier family 3 member 2 (SLC3A2) ( c

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