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Studies have suggested that smoking may be associated with damage to the pancreas, but since smoking may be associated with alcohol use and risk of gallstone disease, it is difficult to note whether smoking is an independent risk factor for the disease

(The chemicals in e-cigarettes are considered maybe safer.) At the same time, a person who is addicted to nicotine can smoke for years or even decades before developing a serious illness, while someone who smokes for a short period may experience severe health effects even after just a year