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Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimers disease-linked presenilin 1 A246E mutation can be reversed with cAMP

This review comprehensively delineates the molecular mechanisms underlying dysregulated iron metabolism in AD and proposes an integrative ironlipidenergyinflammation axis as a pathological framework

A.KumarR.UpadhyayT

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