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Metabolic Changes in Acute Undernutrition and Obesity Despite being on distinctive ends of the nutrition spectrum, acute undernutrition and obesity in childhood both trigger devastating and often intersecting endocrine maladaptations

In early-stage OA , PRP has been found to stimulate chondrogenesis , potentially delaying the need for joint replacement surgery (PMID: 30921868)

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For example, collagen synthesis requires adequate intake of vitamin C, zinc, and specific amino acids like proline and glycine