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The histopathological studies were conducted by sacrificing the animals and collecting the samples directly from the heart and storage at -80C with the estimation of biochemical parameters

TXNRD plays an important role in maintaining the redox balance and has protective role inside dopaminergic cells, which are prone to oxidative stress, e.g., under parkinsonian degeneration (Lopert et al., 2012)

Researchers are still exploring whether pulsatile or continuous GH secretion affects target tissues differently

Most published data comes from animal and laboratory studies, and human clinical trials are lacking, so human efficacy is not established [1]