The FODMAP hypothesis
Other drugs that can cause SJS and TEN include vancomycin, valproate, levofloxacin, etravirine, isotretinoin, quinolones, diclofenac, fluconazole, sitagliptin, oseltamivir, penicillins, barbiturates,sulfonamides, azithromycin, oxcarbazepine, zonisamide, modafinil, pyrimethamine, ethosuximide, bupropion, telaprevir, nystatin, cefixime, and trimethoprim [59]
by increasing mitochondrial generation of reactive oxygen species, promotes hepatocyte apoptosis and recruits inflammatory cells to the liver.30 In ob/ob mice, a model for NAFLD, fatty liver disease is significantly improved by inhibition of TNF-a production.8 Leptin is also produced by adipose tissue in proportion to adipose tissue mass, when leptin action is lacking, whether a consequence of its deficiency or due to leptin resistance, generalized steatosis develops in liver, heart, pancreatic islets, kidneys and skeletal muscle
Aesthetic Protocol: Typically 600mg (1 vial) to 1200mg (2 vials) per session, often mixed in 100mL saline
