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the SHAPS, a 14-item self-rated scale used to measure the state of anhedonia 59 , with higher scores indicating higher levels of anhedonia and the TEPS, an 18-item self-rated scale used to assess anticipatory (TEPS-A) and consummatory components (TEPS-C) of pleasure 60 , with lower scores indicating higher levels of anhedonia

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meaning as the excretion of these metabolites increased, the clinical scores decreased indicating behavioral improvement (Bent et al., 2018)