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Endometriotic lesions are highly vascularized, and it is now widely accepted that the formation of new blood vessels at implantation sites plays a key role in the growth of endometriotic cells [4]

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Curcumin was also found to affect the activity of phase I biotransformation enzymes like cytochrome P450 (CYP) 3A4 (CYP3A4) (118), which catalyzes the metabolism of about one-half of all marketed drugs in the US (119)

NADPH oxidase 4 (NOX4), a ROS-producing enzyme, is highly expressed in the livers of NASH patients and contributes to pathological inflammation and fibrosis in a mouse model of diet-induced NASH (94)