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Description

In vivo tissue distribution of polystyrene or mixed polymer microspheres and metabolomic analysis after oral exposure in mice

Elife 5 , e11288, (2016)

The study identifies how deficiency of the 2-oxoglutarate carrier (Slc25a11) can trigger harmful changes in retinal pigment epithelial (RPE) cellsaccelerating subretinal fibrosis, a major cause of vision loss in neovascular age-related macular degeneration (AMD)