Gene expression signatures of C1-27 and GSTO1 knockdown To identify pathways regulated by GSTO1 and to understand the mechanism of its antiproliferative effects, we used the nascent RNA Bru-seq method 27 to profile gene expression changes that occur in response to GSTO1 knockdown and inhibition
doi: 10.3389/fimmu.2026.1701767 Received 09 September 2025 Revised 16 January 2026 Accepted 19 January 2026 Published 06 February 2026 Volume 17 - 2026 Edited by Uzma Saqib, Devi Ahilya University, India Reviewed by Eduard Yakubov, Paracelsus Medical Private University, Germany Hongjian Pu, University of Pittsburgh, United States Monika Pandey, Devi Ahilya Vishwavidyalaya, India Updates Copyright 2026 Quan, Liu, Zhang, Li, He, Wang, Huang, Zhou, Han and Fan
1 Introduction Arrhythmia arises from disturbances in pulse generation, conduction, or a combination of both, potentially leading to reduced cardiac output or myocardial oxygenation, conditions that can be life-threatening
The FDAs current 503A list places GHK-Cu, except for injectable routes of administration, in Category 1