Their prevalence across research and clinical discussion, not proven superiority in trials, places them at the top of this ranking
One study found that people with migraine with aura (one that causes sensory disturbances like vision changes, blind spots, or flashes of light) who took B vitamin supplements with B6, B9, and B12 had reductions in migraine-related disability from 60% to 30%
Also, reversed was increased number of inflammatory cells (38, 44-46) and raised leukotriene B4 (LTB4), thromboxane B2 (TXB2), and myeloperoxidase (MPO) in the serum and inflamed tissues (47-49)
Do not use while trying to conceive, pregnant, or breastfeeding without medical guidance