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Interestingly, Kv + channels are also important for remyelination ( + channel antagonist that blocks fast K + channels, to a mouse model of cuprizone-induced demyelination, resulted in impaired oligodendrocyte regeneration and remyelination ( Effect of Demyelination on Axonal Transport and Metabolism Axonal transport shuttles critical cell body-derived components back and forth between the soma and axon and across synapses in neurons (Millecamps and Julien, 2013)

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Using stable-isotope tracers, we recently confirmed that obesity-associated glycine deficiency compromised the synthesis and clearance of endogenous and xenobiotic acylCoAs as acylglycines 3