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In clinical practice, prolotherapy is widely used by regenerative medicine physicians and sports medicine specialists for shoulder instability , including: AC joint separation Rotator cuff tendinopathy Multidirectional instability Advantages of Prolotherapy Over Conventional Treatment Prolotherapy empowers the body to repair itself naturally, reducing the need for prolonged medications or surgical intervention

In fact, mitochondrial DNA was identified in exosomes derived from ASP patients and could stimulate cultured human microglia [441]

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