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In transected rat Achilles tendon models, BPC-157 treatment resulted in accelerated recovery with increased load to failure, superior functional scores, enhanced cellular infiltration for repair, better collagen fiber organization, and smaller persistent defects compared to untreated controls

Maximal eccentric exercise induces a rapid accumulation of small heat shock proteins on myofibrils and a delayed HSP70 response in humans

[DOI] [PMC free article] [PubMed] 68.Brenta G, Berg G, Miksztowicz V, Lopez G, Lucero D, Faingold C, Murakami M, Machima T, Nakajima K, Schreier L

However, a Phase I clinical involving monotherapy with 24-h intravenous PX-12 for treating advanced gastrointestinal cancer, while completed, showed no clinical activity but exhibited an atypical toxicity profile [229]