As the primary factors for the reduced anticancer effect 1) the reduced delivery and uptake of the anticancer agent, 2) the need for the conversion of molecular oxygen (O 2 ) into reactive oxygen species (ROS), 3) the preferred therapeutic effect against highly proliferating cells, which is reduced under hypoxic conditions, or 4) adaptation of the cancer cells by promoting cell survival and upregulating certain resistance pathways, has been suggested 1,2,3,4,5
Longevity & Cellular Health Telomere shortening Cellular aging Reduced regenerative capacity Oxidative stress Sleep & Hormonal Balance Poor sleep quality Circadian rhythm disruption Age-related hormonal decline Immune & Cognitive Support Immune resilience Mental clarity Overall vitality Your Epithalon Treatment at Sundrata Personalized Medical Assessment Your provider evaluates longevity goals, sleep quality, and overall metabolic health
Epilepsia 55 , 475482 (2014)
Expanding Therapeutic Applications Research continues to identify new therapeutic targets that may be addressable with peptide-based approaches