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The exception is when a buyer wants very fine dose granularity (e.g., 0.25 mg micro-doses) in which case 3 mL of bac water on a 10 mg vial produces lower concentrations and finer per-unit dose increments at the cost of larger injection volumes

Synthetic B12 (cyanocobalamin) is less bioavailable by comparison and requires a three-step process to be converted to usable B12 in the body

Fifth, and perhaps most practically, the shutdown has reminded everyone that grey-market purchases require a different mindset than buying from established pharmacies