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supplementing with GHK-Cu can have powerful regenerative properties of skin cells

This treatment enhanced the vasculogenesis in a glioma stem cell-dependent manner as evidenced by the elevated expression of CD34 + CD31 + vessel-like structures and an increased abundance of CD133 + CD34 + cells within the tumour core and also facilitated the glioma cells to transdifferentiate into endothelial phenotype [237]

This checkpoint modulation creates permissive conditions for T cell-mediated tumor elimination and provides strong rationale for combining SFN with immune checkpoint inhibitors to overcome therapeutic resistance