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6, September: 3083-3092, 2018 Patients and Methods: This study included 30 female patients with melasma who were selected among those attending the Outpatient Clinic of Dermatology and Venereology De- partment, Tanta University Hospitals during the period between December, 2015 and February, 2017

14 2026 May : Added section titled Terminology Update: Polycystic Ovary Syndrome (PCOS) Is Now Known as Polyendocrine Metabolic Ovarian Syndrome (PMOS) to Overview 2024 Dec : Updated content on non-classical congenital adrenal hyperplasia (NC-CAH) in Diagnosis of Polycystic Ovary Syndrome 2022 Feb : Comprehensive update & review 2021 Apr : Added section on curcumin to Nutrients Disclaimer and Safety Information This information (and any accompanying material) is not intended to replace the attention or advice of a physician or other qualified health care professional

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75 Additionally, fructooligosaccharides and galactooligosaccharides alleviate MASLD by increasing the abundance of acetate-producing bacteria (such as Bacteroides acidifaciens and Bacteroides dorei ) and inducing POMC/GPR43-positive neurons in the hypothalamic arcuate nucleus, indicating the existence of gut microbiota-brain axis signal regulation